Liver flukes are parasitic flatworms that infect the bile ducts and liver, most commonly species such as Fasciola hepatica and Clonorchis sinensis. Humans typically acquire infection by consuming contaminated water or raw or undercooked aquatic plants or fish containing larval stages of the parasite. Once inside the body, the flukes migrate to the liver and bile ducts, where they can cause inflammation, abdominal pain, fever, fatigue, jaundice, and digestive disturbances. Chronic infection may lead to bile duct obstruction, liver enlargement, or increased risk of bile duct cancer in certain species. Diagnosis is usually made through stool examination or imaging studies, and treatment involves specific antiparasitic medications to eliminate the infection.